每周在联赛或者国际赛场中表现最为出色的球员都会入选EA每周最佳阵容。玩家可以在Ultimate Team模式中挑战周最佳阵容而获得游戏金币。同时玩家可以在该周内通过抽包的形式获得这些球员卡，这些卡片极具收藏价值。

首发阵容：

GK: Diego Alves – Valencia CF (Spain)

CB: Laurent Ciman – Standard Liège (Belgium)

CB (RB): Mikael Lustig – Celtic (Scotland)

LM (CM): Julien Féret – SM Caen (France)

CM (CDM): David Pizarro – Fiorentina (Italy)

CM (CAM): Wesley Sneijder – Galatasaray SK (Turkey)

RM: Dirk Kuyt – Fenerbahçe SK (Turkey)

LW: Neymar – FC Barcelona (Spain)

ST: Miroslav Klose – Lazio (Italy)

RW (ST): Ross McCormack – Fulham (England)

替补阵容：

GK: Romain Salin – Marítimo (Portugal)

CB: Miguel Ángel Herrera – Pachuca (Mexico)

RM: Stéphane Darbion – ES Troyes AC (France)

LM: Sam Larsson – SC Heerenveen (The Netherlands)

ST: Odion Ighalo – Watford (England)

ST: Jonathan Pereira – Real Valladolid (Spain)

ST: Kris Doolan – Partick Thistle (Scotland)